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ME and CFS...It's in your mind!..is it?

It's not all in your head


Hi, Julies husband here again (pete)
i'm affraid Julie has had a relapse this evening, and at present is lying on the bed with her dinner in the microwave. In her eagerness to help fellow sufferers she's overdone it the last couple of days and as you all know at some time you pay back, and today is " payback time". Whilst she is getting some well earned rest I will proceed to explain in part why julie is in bed right now!.

For many years sufferers of CFS/ME have been told it's all in the mind and prescribed anti-depressant medication. Sometimes they've been told to pull themselves together and get on with it. It can now be shown that extreme fatigue experienced by CFS/ME sufferers is a direct result of mitochondrial dysfunction i.e.dysfunction in the energy production mechanism of our bodies and has very little to do with " it's in your mind ".
Mitochondria - It's Functions.
This is where it gets technical but bare with me, the job of the mitochondria is to supply energy in the form of ,wait for it, ATP this is the universal unit of energy within every cell. It can be used for all sorts of biochemical jobs from muscle contraction to hormone production. When mitochondria fail to function correctly it results in a poor supply of ATP, so cells go slow because they don't have the energy supply to function at normal speed. Does this sound familiar , it means that all bodily functions slow down.
This is where it gets even more technical but hang on in there! ATP is converted into something called ADP with the release of energy for work. ADP is passed into the mitochondria where ATP is remade. This recycling occurs approximately every 10 seconds in a normal person. If this slows down then the person slows down and suffers with poor stamina as in CFS/ME.
If the CFS/ME sufferers calls for energy faster than the body can supply it ATP is converted to ADP faster than it can be recycled. This means a build up of ADP , this in turn is converted into something called AMP, here lies the problem AMP cannot be recycled and is lost in urine.
Therfore one can only go at the rate at which mitochonria can produce ATP. So if mitochondria goes slow,stamina becomes low. If ATP levels drop quickly as a result of AMP loss, the body then has to make brand new ATP. ATP can be made very quickly from a sugar called D-ribose, but D-ribose is only slowly made from glucose, this can take anything between 1 to 4 days and is the reason why many sufferers of CFS/ME suffer setbacks, as in Julies recent case, some days after over doing things.
If the body is very short of ATP it can make small amounts directly from glucose stored in our bodies by converting it into lactic acid. This is what CFS/ME sufferers do and this results in lactic acid building up in muscles causing pain, heaviness and soreness. Secondly little glucose remains available to make D-ribose so new ATP cannot be easily made and therefore recovery takes days and the cycle goes on.
It all makes sense and explains alot of the difficulties sufferers experience when they start to feel a little better and push a little too hard.
At the end of this blog I will include a web address where you can read in more detail; it really is interesting although at times hard going.
What can be done to help the mitochondria ?

Do not use energy faster than your mitchondria can supply it, this requires pacing, pacing your activities to avoid undue stress of the mitochondria,
Do a little and rest.
Supply the raw material necessary for the mitochondria to heal themselves and work more efficiently.
Take a good range of micronutrient supplements.
Stabalise blood sugar levels.
Identify allergies to food.

Getting excellent sleep so the mitochondria can repair-using meditation tapes or relaxing music which helps Julie.
Address the damage caused by mitochondria failure such as immune disturbances resulting in allergies, poor digestive functions and slow liver detoxification.
Detoxifying to unload heavy metals, pesticides alcohol and drugs.
To help with detoxification i've included some of natures best antioxidants.
Fruit- Berries ( blueberry, blackberry, strawberry, raspberry, black current, bilberry,) pomegranate, grape,cherry .
Vegetables: Kale, chilli pepper, red cabbage, peppers, brocolli,sprouts,spinach,corriander,artichoke.
Dry Fruit: apricots, prunes, dates.
Lugum es: Broad beans, pinto beans, soybean.
Nuts & Seeds: Pecans,walnuts,hazelnuts,sunflower seeds,peanuts.
Cereals:Barley, millet,oates,corn.
Spices: Cloves, cinnamon, oregan.
I hope you found this interesting and it explains to you the complexities of CFS/ME and, when time permits, I hope to do a blog on toxins in our body and in our food.
Here is the link if you want to read about it in greater detail.
put in google search CFS -The Central Cause:Mitochondrial Failure
From Doctor Myhill or www.drmyhill.co.uk/.../CFS_-_The_Central_Cause:_Mitochondrial_Failure

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